CSS: The Surprising Truth About Pixels and Accessibility: should I use pixels or rems?
The truth is, if you want to build the most-accessible product possible, you need to use both pixels and ems/rems. It’s not an either/or situation. There are circumstances where rems are more accessible, and other circumstances where pixels are more accessible.
Source: The Surprising Truth About Pixels and Accessibility: should I use pixels or rems?